The control groups were allocated

Categories of trialThe trials were divided into three predefined categories according to whether the recruitment was based on participants having no history of cardiovascular disease, a history of CHD (acute myocardial infarction, coronary artery disease without recent infarction, or heart failure), or a history of stroke (or other cerebrovascular disease). In the trials of participants with no history of vascular disease, blood pressure was usually high, variably defined, and a treat to target approach was used, typically based on one drug with the dose increased before the addition of other drugs to reach the target blood pressure. The control groups were allocated to usual care.

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